Ig lambda chain V-I region pseudogene

The “Ig lambda chain V-I region pseudogene” (ENSG00000249333) is a noncoding genetic sequence found within the immunoglobulin lambda light chain gene locus. Immunoglobulin lambda chains are one of the two classes of antibody light chains in humans and play a critical role in the formation of antigen-binding sites. However, this specific gene is a pseudogene, meaning it contains mutations or sequence defects that prevent it from encoding a functional immunoglobulin protein. Pseudogenes in this locus often arise from gene duplication and recombination events but are generally not expressed or simply produce nonfunctional RNA transcripts. This pseudogene lacks disease relevance, known biological function, and established therapeutic interaction. The name may be confusing for therapeutic research, as only functional immunoglobulin genes or proteins are considered valid biological targets[1][3][4][5][6].

Other names

IG lambda chain V region pseudogeneIG lambda chain pseudogeneHomo sapiens pseudo-lambda Ig pseudogene