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Ig lambda chain variable region pseudogene

Molecular classification
Other (pseudogene, immunoglobulin-related)
01

Overview

Ig lambda chain variable region pseudogenes are nonfunctional gene segments within the immunoglobulin lambda light chain locus. They do not encode functional antibody proteins and do not participate in normal immune responses. Pseudogenes arise from gene duplication and mutation events, and, while they are related to the structure and evolution of the immunoglobulin gene family, they have no direct biological activity or therapeutic relevance. This entry is labeled and recognized as a pseudogene, meaning it is not translated into a functional protein and does not participate in any canonical biological pathways or serve as a drug target. The presence of such pseudogenes is important in the genomic architecture of antibody loci but has no direct disease role, drug interaction, or biomarker relevance. The pseudogene label means the entry is not considered a therapeutic target, and its inclusion as a "target" is incorrect.

Other names
Ig lambda V pseudogeneVλ pseudogenepsi Vλpseudogene V lambda

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