IL1R1 antisense RNA 1 (IL1R1-AS1)

IL1R1 antisense RNA 1 (IL1R1-AS1) is a long noncoding RNA gene transcribed in the antisense orientation to the interleukin-1 receptor type 1 (IL1R1) gene. While lncRNAs of the antisense type often regulate the expression of their sense (protein-coding) counterparts, such as by altering chromatin structure, affecting transcription, or forming RNA duplexes to influence mRNA stability, there is no direct evidence for a unique protein product or direct therapeutic targeting of IL1R1-AS1. Like other antisense lncRNAs, IL1R1-AS1 could play a role in regulating inflammation and immune responses by modulating the expression of the IL1R1 receptor or related genes. However, its specific biological functions, disease relevance, and potential as a clinical biomarker or therapeutic target are currently not well characterized in the scientific literature. No search results yielded primary research directly on IL1R1-AS1; this answer leverages standard knowledge about antisense lncRNAs and recognized genomic annotations. If more detailed functional data or disease links arise, these fields can be updated accordingly.

Other names

AC007271.3IL1R1-AS1