Target intelligence / Profile preview

Immune Cell Receptor

Molecular classification
Receptor, Transmembrane protein
01

Overview

A class of membrane-bound or intracellular proteins expressed by immune cells that recognize specific ligands—including pathogen-associated molecular patterns, peptide-MHC complexes, antibodies, complement fragments or cytokines—to initiate cellular activation and coordinate innate/adaptive immunity.

Other names
Immunologic Receptor
02

Mechanism of action

Agonism, antagonism, immune modulation

03

Biological functions

Pathogen detectionImmune responseSignal transductionCell activationRegulation of immune response
04

Disease associations

InfectionAutoimmune diseaseCancerInflammation
05

Safety considerations

Cytokine stormImmunosuppressionOff-target effectsAutoimmunity

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