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Immune Response Mediator

Molecular classification: Cytokine, Chemokine, Lipid Mediator, Complement Component, Acute Phase Protein, Receptor

Overview

Immune response mediators are molecules that regulate, initiate, amplify, or resolve immune responses. These mediators are essential for communication between cells of the immune system and for orchestrating both innate and adaptive immunity. They include a diverse array of soluble factors such as cytokines, chemokines, lipid mediators (e.g., leukotrienes), complement components, and other signaling molecules.

Mechanism of action

Binding to specific receptors on target cells to trigger intracellular signaling cascades.

Biological functions

Immune responseInflammationHost defenseCell signalingCell recruitmentTissue repair

Disease associations

AutoimmunityAllergyImmunodeficiencyInfectionChronic inflammatory diseases

Safety considerations

Excessive mediator activity can cause chronic inflammatory diseases/allergies.Insufficient activity can result in immunodeficiency/increased infection risk.

Interacting drugs

Monoclonal antibodies against cytokines/receptors

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