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Immune system (T-cell Activation)

Molecular classification: Other

Overview

T-cell activation is a fundamental process in the adaptive immune response, enabling T cells to recognize and respond to pathogens, infected cells, or abnormal cells such as cancer. This process is initiated when T cells encounter antigen-presenting cells (APCs) that display specific antigens bound to major histocompatibility complex (MHC) molecules on their surface.

Mechanism of action

Enhancing co-stimulation, blocking inhibitory checkpoints, or dampening inappropriate activation.

Biological functions

Immune response

Disease associations

CancerInfectionAutoimmunityImmunodeficiency

Safety considerations

ImmunodeficiencyAutoimmunityCytokine release syndrome

Interacting drugs

Cancer immunotherapies (e.g., checkpoint inhibitors)

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