Target intelligence / Profile preview

Immune System - Immunomodulation

Molecular classification
Biological Process, Therapeutic Target
01

Overview

Immunomodulation refers to the process of adjusting or regulating the immune system’s activity, either by enhancing or suppressing its responses. This can occur naturally within the body to maintain homeostasis, or it can be induced therapeutically to treat diseases such as autoimmune disorders, cancers, and in transplantation medicine.

Other names
ImmunomodulationImmune Regulation
02

Mechanism of action

Immunomodulators work at multiple levels: - Gene transcription affecting lymphocyte function - Regulation of humoral response including antibody production - Modulating release/action of inflammatory mediators like cytokines/histamine Some interventions aim to boost underactive immunity while others suppress overactivity depending on clinical need.

03

Biological functions

Regulation of immune responsesEnhancement of immune responsesSuppression of immune responsesHomeostasis maintenance
04

Disease associations

Autoimmune diseasesCancerAllergiesTransplant rejectionImmunodeficiencyInflammation
05

Interacting drugs

Corticosteroids

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