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Immune Response/Inflammation Pathway
- Molecular classification
- Pathway, Network
01
Overview
The immune response/inflammation pathway is a complex network of molecular and cellular events that protect the body from harmful stimuli, such as pathogens, toxins, or tissue injury. This pathway involves the coordinated activation of immune cells, blood vessels, and molecular mediators to eliminate threats and initiate tissue repair. Chronic dysregulation of this pathway contributes to diseases such as cardiovascular disease, diabetes, arthritis, and cancer. Persistent activation leads to tissue damage due to prolonged mediator release and immune cell infiltration.
- Other names
- Inflammatory PathwayImmune System ActivationInflammation
02
Mechanism of action
Multiple mechanisms involved in regulating immune cell activation, cytokine production, and inflammation.
03
Biological functions
Immune responseInflammationTissue repairHost defense
04
Disease associations
Cardiovascular diseaseDiabetesArthritisCancerInflammationAutoimmune diseases
05
Safety considerations
ImmunosuppressionIncreased risk of infectionOff-target effects on other immune pathways
06
Biomarkers
Cytokine levels (e.g., IL-1β, IL-6, TNF-α)C-reactive protein (CRP)Erythrocyte sedimentation rate (ESR)White blood cell count
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