Target intelligence / Profile preview

Immune System Modulators

Molecular classification
Cytokine, Monoclonal Antibody, Vaccine, Small Molecule Drug, Biologic
01

Overview

Immune system modulators are substances or drugs that alter the activity of the immune system. They can either stimulate (immunostimulation) or suppress (immunosuppression) immune responses to help the body fight diseases such as cancer, infections, and autoimmune disorders. They encompass a wide range of agents with diverse mechanisms, targeting various components and pathways within the innate and adaptive immune systems.

Other names
ImmunomodulatorsImmunostimulantsImmunosuppressants
02

Mechanism of action

Enhance/suppress cell-mediated/humoral immunity through diverse molecular/cellular targets

03

Biological functions

Immune responseInflammationCell signalingAntigen presentationModulation of cytokine productionRegulation of immune cell activity
04

Disease associations

CancerAutoimmune diseasesInflammatory disordersInfection
05

Safety considerations

FatigueGastrointestinal symptoms (nausea, vomiting, diarrhea, loss of appetite)Rash or skin reactionsIncreased risk of infection (with immunosuppressants)
06

Interacting drugs

Interferon-alpha

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