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Immune tolerance induction
- Molecular classification
- Other
01
Overview
Immune tolerance induction refers to the physiological processes by which the immune system becomes unresponsive (tolerant) to specific antigens, preventing harmful immune reactions against self-tissues (autoimmunity), transplanted organs, allergens, or other non-threatening substances. This state of unresponsiveness can be naturally established during development (central tolerance) or actively maintained in peripheral tissues throughout life (peripheral tolerance).
02
Mechanism of action
Interrupting effector pathways, Restraining innate activation, Enhancing regulatory networks
03
Biological functions
Immune responseTolerance inductionRegulation of immune system process
04
Disease associations
Autoimmune DiseasesTransplant RejectionAllergyCancerInfection
05
Safety considerations
Chronic immunosuppressionEvasion strategy of tumorsBenefit for pathogens
06
Interacting drugs
Immunosuppressive drugs
1 more in the full profile.
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