Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Immunoglobulin Beta (Igβ)
- Target
- Igβ
- Molecular classification
- Transmembrane glycoprotein, Receptor
01
Overview
Igβ, also known as CD79b, is a transmembrane protein and a crucial component of the B cell receptor (BCR) complex. It forms a heterodimer with Igα (CD79a), and together they are essential for both the surface expression and signaling functions of the BCR in B lymphocytes. Upon antigen binding to mIg, ITAMs in both Igα and Igβ become phosphorylated. This phosphorylation recruits downstream effectors such as Syk kinase. Both chains are required for proper maturation signals and allelic exclusion. The complex mediates internalization of bound antigen for processing and presentation to T cells.
- Other names
- CD79b
02
Biological functions
Signal transductionB cell developmentAntigen presentationEndocytosisImmune response
03
Disease associations
B-cell lymphomasAutoimmune diseases
04
Safety considerations
Potential for off-target effects on B cell functionImmunosuppression
Beyond the preview
Go deeper on Immunoglobulin Beta (Igβ).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Immunoglobulin Beta (Igβ).