Target intelligence / Profile preview

Immunoglobulin G (IgG)

Target
IgG
Molecular classification
Antibody, Immunoglobulin
01

Overview

Immunoglobulin G is essential for adaptive immunity due to its abundance, versatility against diverse antigens/pathogens across tissues—including placental transfer—and its diagnostic value in clinical medicine through quantitative assays assessing both deficiency states and abnormal proliferations.

Other names
IgG antibodyGamma globulin
02

Mechanism of action

N/A

03

Biological functions

NeutralizationOpsonizationComplement activationAntibody-dependent cell-mediated cytotoxicity (ADCC)Passive immunityHumoral immune response
04

Disease associations

Chronic infectionAutoimmune diseaseLiver diseaseMultiple myelomaMonoclonal gammopathiesImmunodeficiency
05

Biomarkers

Serum IgG levels

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