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Target intelligence / Profile preview
Immunoglobulin heavy joining 1 pseudogene (IGHJ1P)
- Target
- IGHJ1P
- Molecular classification
- Other (Pseudogene, Immunoglobulin joining gene segment family)
01
Overview
Immunoglobulin heavy joining 1 pseudogene (IGHJ1P) is a nonfunctional member of the immunoglobulin heavy chain joining segment family, present at the IGH locus on chromosome 14. Unlike the closely related IGHJ1 gene, IGHJ1P does not encode a protein and does not participate in V(D)J recombination or antibody synthesis[1][7]. The protein-coding joining segments (such as IGHJ1) are essential parts of the immunoglobulin complex in B lymphocytes, contributing to antigen recognition. The IGHJ1P sequence is typically annotated in genomic studies for completeness, but it is irrelevant to therapeutic targeting, biomarker studies, or drug interaction research[1][7]. The use of IGHJ1P as a therapeutic target or functional marker is incorrect.
- Other names
- Jpsi1J-psi-1IGHJ1P
02
Mechanism of action
None relevant for IGHJ1P.
03
Biological functions
None for IGHJ1P itself (as a pseudogene)
04
Disease associations
None directly for IGHJ1P
05
Safety considerations
None for IGHJ1P
06
Interacting drugs
None
07
Biomarkers
None for IGHJ1P
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