Immunoglobulin heavy variable (III)-16-1 (pseudogene) (IGHVIII-16-1)

Immunoglobulin heavy variable (III)-16-1, abbreviated as IGHVIII-16-1, is a **pseudogene** in the human genome, specifically classified as a non-functional gene segment related to the variable region of the immunoglobulin heavy chain[4][6]. Unlike productive immunoglobulin heavy variable genes, this pseudogene does not encode a functional protein due to sequence alterations that prevent the generation of a productive antibody chain. As a result, it neither serves as a target for therapeutic intervention nor holds established biological functions or disease associations. It exists as part of the extensive immunoglobulin gene locus, which encodes components for antibody diversity, but this particular sequence is **non-functional** in the production of functional immunoglobulins[2][4][6].

Other names

IGHV(III)-16-13-16.1PIGHVIII161IGHVIII-16-1