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Immunoglobulin heavy variable 7-40 (IGHV7-40)
- Target
- IGHV7-40
- Molecular classification
- Other (Immunoglobulin variable gene segment pseudogene)
01
Overview
Immunoglobulin heavy variable 7-40 (IGHV7-40) is a classified pseudogene in the human immunoglobulin heavy chain variable region locus[4][5]. Pseudogenes like IGHV7-40 are incomplete or non-functional copies of genes and do not produce functional protein products. While related functional genes in the immunoglobulin heavy chain locus are critical components of antibody diversity, IGHV7-40 itself does not contribute to antigen binding or immune function. IGHV7-40 does not encode a functional variable region of antibody heavy chain, is not a therapeutic target, receptor, enzyme, or transporter, and no drugs interact with or target this pseudogene. No disease roles or biomarker applications are described for IGHV7-40. If the intent is to refer to a functional immunoglobulin heavy chain variable gene, information on functional IGHV segments (such as IGHV7-4-1 or others), which are involved in immune recognition and have well-described biological roles and structure[2][1], should be sought instead.
- Other names
- Immunoglobulin heavy chain variable region 7-40IGHV7-40immunoglobulin heavy variable region 7-40
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