Target intelligence / Profile preview

Immunoglobulin kappa variable 1D-13 (IGKV1D-13)

Target
IGKV1D-13
Molecular classification
Other (Immunoglobulin variable domain)
01

Overview

Immunoglobulin kappa variable 1D-13 is the V (variable) region of the light chain of immunoglobulins (antibodies), participating in antigen recognition. It is a structural component of the immunoglobulin complex produced by B lymphocytes. Immunoglobulin variable domains confer specificity to antibody-antigen binding, enabling the humoral immune response. This gene encodes only the variable domain, with its biological function limited to enabling antigen recognition through formation of the antibody binding site. The protein is expressed as part of membrane-bound or secreted immunoglobulins and not as an independent functional receptor or enzyme. There is no evidence for direct targeting by drugs or use as a therapeutic target[1][2][3][5][7][11].

Other names
IGKV1D-13IGKV1D13L18KVD13
02

Biological functions

Immune responseAntigen recognition
03

Disease associations

Other (no direct evidence as disease target; role is in humoral immunity)

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