Immunoglobulin kappa variable 2D-18 pseudogene (IGKV2D-18)

Immunoglobulin kappa variable 2D-18 pseudogene (IGKV2D-18) is a member of the immunoglobulin kappa variable (IGKV) gene family, located within the immunoglobulin kappa locus (IGK) at chromosome 2p11.2[8][9]. The IGKV gene family encodes the variable domain of the kappa light chains of immunoglobulins (antibodies), which are crucial for antigen recognition, through the process of V-J rearrangement during B cell development[1][3][5][9]. IGKV2D-18 is annotated as a pseudogene, meaning it is a DNA sequence similar to a functional gene but is not translated into a functional protein product—usually due to mutations or lack of essential coding segments[2][4][9]. As such, it does not have a known protein product, is not considered a therapeutic target, and is not directly implicated in disease or used as a biomarker. Alternative names include A13 and IGKV2D18[2][4].

Other names

A13IGKV2D18IGKV2D-18