Immunoglobulin kappa variable 2D-26 (IGKV2D-26)

Immunoglobulin kappa variable 2D-26 (IGKV2D-26) is a human pseudogene belonging to the kappa light chain variable region gene family of immunoglobulins. It encodes the V (variable) domain of immunoglobulin light chains, which are essential for antigen recognition in functional immunoglobulins. However, IGKV2D-26 itself is annotated as a pseudogene, meaning it does not produce a functional protein. The immunoglobulin variable region genes, when functional, mediate antigen binding as part of the body's humoral immune response, but IGKV2D-26 does not encode a functional antibody chain and is not known to have therapeutic or biomarker relevance[1][2][5]. Clarification: IGKV2D-26 is a pseudogene—not a functional receptor, enzyme, transporter, or common therapeutic target. Its classification as a pseudogene means it does not encode a functional protein product and therefore is not druggable or directly linked to disease mechanisms, drug interactions, or safety concerns[1][2][5].

Other names

IGKV2D-26A5IGKV2D26Immunoglobulin kappa variable 2D-26immunoglobulin light chain variable region

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