Immunoglobulin kappa variable 3D-11 (IGKV3D-11)

Immunoglobulin kappa variable 3D-11 (IGKV3D-11) is the gene encoding a variable domain of the kappa-type light chain in human immunoglobulins (antibodies)[1][3][5][9]. The variable region is assembled through V(D)J recombination and contributes to the formation of the antigen-binding site, thereby determining antibody specificity for antigens[5][9]. IGKV3D-11 itself is not a receptor, enzyme, or drug target, but is a segment used in the genetic recombination process that equips antibodies with diversity for humoral immune responses[5]. Immunoglobulin variable domains like IGKV3D-11 are essential for the adaptive immune system and may be referenced in studies of immune repertoire or monoclonal antibody development, but they are not generally considered direct drug targets nor do they have direct biomarker, drug interaction, or safety concern associations[5][9].

Other names

IGKV3D-11IGKV3D11L20Immunoglobulin kappa variable 3D-11