Target intelligence / Profile preview

Immunoglobulin kappa variable 5-2 (IGKV5-2)

Target: IGKV5-2
Molecular classification: Immunoglobulin, Antibody, Variable region of immunoglobulin light chain

Overview

Immunoglobulin kappa variable 5-2 is the V region of the variable domain of immunoglobulin light chains, participating in antigen recognition as part of the antigen-binding site in antibodies. This region is critical for the recognition phase of humoral immunity and enables B lymphocytes to detect and bind specific antigens, triggering immune responses including clonal expansion and the formation of plasma cells that secrete immunoglobulins to help eliminate antigens[1][2][5][8].

Other names: IGKV52B2Ig kappa chain V region EV15IGKV5-2

Biological functions

Antigen recognitionImmune responseAntigen binding

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Other

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