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Target intelligence / Profile preview
Immunoglobulin kappa variable 7-3 (IGKV7-3)
- Target
- IGKV7-3
- Molecular classification
- Other (Pseudogene, immunoglobulin variable region gene family)
01
Overview
Immunoglobulin kappa variable 7-3 (IGKV7-3) is a member of the kappa light chain variable gene family located within the immunoglobulin kappa locus on chromosome 2p11.2 in humans. Like other variable region genes, it forms part of the genomic repertoire that can contribute to generating antibody diversity, though IGKV7-3 itself is a pseudogene, meaning it does not encode a functional immunoglobulin protein. Pseudogenes such as IGKV7-3 are non-functional due to mutation, recombination, or other genomic alterations and thus are not involved directly in immune function or disease. This gene, as is standard for pseudogenes in the immunoglobulin gene cluster, does not serve as a therapeutic drug target and is not used for pharmacological intervention or clinical biomarker purposes.
- Other names
- Immunoglobulin kappa variable region 7-3IGKV7-3
02
Mechanism of action
None. No drugs target this gene, so no mechanism of action is available
03
Biological functions
None. As a pseudogene, it does not encode a functional protein
04
Disease associations
None. There is no established direct disease role for IGKV7-3 as a pseudogene. Pseudogenes generally are not directly involved in pathology
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