Immunoglobulin lambda constant 3 (IGLC3)

Immunoglobulin lambda constant 3 (IGLC3) encodes the constant region of the lambda light chain in human immunoglobulins (antibodies)[2][7]. Immunoglobulins are membrane-bound or secreted glycoproteins produced by B lymphocytes, and they mediate the humoral immune response by binding antigens, leading to elimination of pathogens. IGLC3 is predicted to enable antigen binding and participate in immunoglobulin-mediated immune responses[1][2][7]. The gene is expressed across various tissues and is a component of blood microparticles and extracellular exosomes[1][6]. IGLC3 is not itself a direct therapeutic target, receptor, or enzyme, but rather a structural part of antibodies, which are commonly exploited in therapy as whole molecules rather than as isolated constant regions[1][2][7].

Other names

immunoglobulin lambda constant 3 (Kern-Oz+ marker)IGLCC3 segmentIg lambda chain C region DOTIg lambda chain C region NEWMIg lambda-3 chain C regionIg lambda-3 chain C regionsimmunoglobulin lambda constant region 3 (Kern-Oz+ marker)