Target intelligence / Profile preview

Immunoglobulin lambda variable 2-11 (IGLV2-11)

Target
IGLV2-11
Molecular classification
Immunoglobulin variable domain, Other
01

Overview

Immunoglobulin lambda variable 2-11 (IGLV2-11) encodes the variable region of the lambda light chain of immunoglobulins, a component of antibodies produced by B lymphocytes. This variable region forms part of the antigen-binding site, which confers specificity to antibody-antigen interactions. IGLV2-11 is integral to the immune system’s ability to recognize a broad array of foreign antigens but is not itself a therapeutic target, receptor, enzyme, or transporter. Instead, it serves mainly as a structural genetic unit within the immunoglobulin light chain locus, enabling the diversity and specificity of antibody-mediated immune responses[1][2][3][4][5][8].

Other names
IGLV2-11Ig lambda chain V-II region BOHIg lambda chain V-II region DOTIg lambda chain V-II region BURIg lambda chain V-II region NIG-58Ig lambda chain V-II region TROIg lambda chain V-II region WINV1-3IGLV211
02

Biological functions

Antigen recognitionImmune response
03

Disease associations

Other (no direct or prominent disease linkage as a drug target)

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