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Immunoglobulin lambda variable 2-5 (IGLV2-5)

Target: IGLV2-5
Molecular classification: Other (Pseudogene of Immunoglobulin variable domain family)

Overview

Immunoglobulin lambda variable 2-5 (IGLV2-5) is a human pseudogene belonging to the immunoglobulin lambda variable (IGLV) gene family, which ordinarily encodes variable domains of antibody light chains. As a pseudogene, IGLV2-5 does not produce a functional protein product and plays no active role in the immune response or antibody formation. It is part of the lambda light chain locus that includes both functional and non-functional (pseudo)genes. The functional IGLV genes contribute to the diversity of antibody recognition, but IGLV2-5 has lost coding potential due to disabling mutations. It is not regarded as a receptor, enzyme, or any other canonical druggable target.

Other names: immunoglobulin lambda variable 2-5 (pseudogene)IGLV2-5 (pseudogene)

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