Immunoglobulin lambda variable 4-3 pseudogene (IGLV4-3P)

The immunoglobulin lambda variable 4-3 pseudogene (IGLV4-3P) is a non-functional segment of DNA within the immunoglobulin lambda light chain variable region gene family in humans. Pseudogenes such as IGLV4-3P result from mutations rendering the gene incapable of producing a functional immunoglobulin protein. While functional immunoglobulin variable genes encode the antigen-binding domains of antibodies essential for adaptive immunity, pseudogenes like IGLV4-3P are not transcribed into protein and are not involved in immune function. These loci are typically noted only in molecular studies and genetic annotation; they do not serve as therapeutic targets in current pharmacology or immunology[1][2][6].

Other names

IGLV43V5-1