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Target intelligence / Profile preview
Immunoglobulin lambda variable 4-60 (IGLV4-60)
- Target
- IGLV4-60
- Molecular classification
- Immunoglobulin variable region, Immunoglobulin light chain domain, Other
01
Overview
Immunoglobulin lambda variable 4-60 (IGLV4-60) encodes the variable region of the lambda light chain of human immunoglobulins, which is involved in antigen recognition as part of the adaptive immune response[4][2]. This gene belongs to the immunoglobulin lambda variable family and is expressed in B lymphocytes, where its variable region contributes to the diversity of antibody specificity through V-(D)-J gene rearrangement[2][3]. IGLV4-60 is not a therapeutic target by itself, but rather a genetic segment used in the assembly of antibodies, which can be further diversified in response to antigen exposure[4].
- Other names
- IGLV4-60IGLV460V5-4Immunoglobulin lambda variable 4-60
02
Biological functions
Antigen recognitionAdaptive immune response
03
Disease associations
Other
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