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Immunoglobulin lambda variable 5-48 pseudogene (IGLV5-48 (pseudogene))
- Target
- IGLV5-48 (pseudogene)
- Molecular classification
- Pseudogene, Immunoglobulin variable region pseudogene
01
Overview
Immunoglobulin lambda variable 5-48 pseudogene (IGLV5-48) is a member of the immunoglobulin lambda variable (IGLV) gene family located in the immunoglobulin lambda locus. As a pseudogene, IGLV5-48 represents a non-functional open reading frame that does not encode a functional variable region of an immunoglobulin light chain. It likely became non-functional due to alterations in its coding sequence or recombination/splicing signals. While the broader IGLV family is essential for antigen recognition by antibodies (immunoglobulins) during immune responses, pseudogenes like IGLV5-48 do not participate in immunoglobulin synthesis, V(D)J recombination, or immune effector functions[4][5][7].
- Other names
- IGLV5-48Immunoglobulin lambda variable 5-48 (pseudogene)
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