Target intelligence / Profile preview

Immune system

Molecular classification
Other (not a single molecule, receptor, or protein family)
01

Overview

The **immune system** is not a single molecule or receptor but rather a complex network of cells, tissues, organs, and molecular mediators that work together to protect an organism from disease. It consists of two main branches: *Innate immune system*: Provides immediate but non-specific defense against pathogens through mechanisms such as physical barriers, phagocytic cells (e.g., neutrophils, macrophages), pattern recognition receptors like toll-like receptors (TLRs), cytokines, chemokines, and the complement cascade. This branch does not confer long-lasting immunity but is essential for initial pathogen control[7]. *Adaptive immune system*: Mounts specific responses to antigens via lymphocytes—B cells produce antibodies while T cells mediate cellular immunity. Adaptive responses are slower to develop on first exposure but provide immunological memory for faster response upon re-exposure. Molecular components include antibodies of various classes (IgM, IgG, IgA, IgD, IgE), cytokines such as interleukins and interferons that regulate cell communication during immune responses; chemokines that direct cell migration; pattern recognition receptors like TLRs; antigen-presenting molecules such as MHC proteins; and numerous other soluble factors involved in inflammation or tolerance[1][2][7]. Because "Immune system" refers to an entire biological network rather than a discrete molecular target or receptor suitable for drug targeting in the conventional sense—and encompasses many different molecules with distinct roles—it is not considered a canonical therapeutic target itself. Instead, individual components within the immune system may serve as drug targets depending on context. If you are seeking information about a specific molecule within the immune system—such as "Programmed cell death protein 1" or "Interleukin 6 receptor"—please specify so structured data can be provided at the appropriate level of detail.

Other names
Immune systemHuman immune systemImmunological system
02

Biological functions

Immune responsePathogen recognition and eliminationInflammation regulationTissue homeostasis maintenanceAntigen presentationCytokine production and signaling
03

Disease associations

Cancer (via immune surveillance and tumor microenvironment interactions)Infection (defense against pathogens)Inflammation (acute and chronic responses)Autoimmunity (when dysregulated)

Beyond the preview

Go deeper on Immune system.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Immune system.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call