Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Immunomodulation via allogeneic expanded adipose-derived stem cells (ASCs (Allogeneic Expanded))
- Target
- ASCs (Allogeneic Expanded)
- Molecular classification
- Cell Therapy, Stem Cell Therapy, Immunomodulatory Agent
01
Overview
Allogeneic expanded adipose-derived stem cells (ASCs) are used for their immunomodulatory effects in treating inflammatory and autoimmune diseases. They function through cell contact and paracrine signaling, releasing anti-inflammatory cytokines and growth factors. Clinical applications include Crohn's disease, rheumatoid arthritis, and other conditions. Challenges include donor variability and the need for further research to optimize clinical use.
- Other names
- Allogeneic Adipose-Derived Stem CellsExpanded ASCsAllogeneic ASCs
02
Mechanism of action
Immunomodulation via cell contact-dependent mechanisms and paracrine effects through soluble factors (e.g., IL-10) secreted by ASCs.
03
Biological functions
ImmunomodulationAnti-inflammatory activityTissue regenerationRegulation of immune cell function
04
Disease associations
Autoimmune diseasesInflammatory diseasesFistulizing diseasesGraft-versus-host disease
05
Safety considerations
Potential for immune rejectionVariability in ASC immunosuppressive function based on donor characteristics (e.g., BMI, diabetes)Risk of ectopic tissue formationLimited long-term safety data
Beyond the preview
Go deeper on Immunomodulation via allogeneic expanded adipose-derived stem cells (ASCs (Allogeneic Expanded)).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Immunomodulation via allogeneic expanded adipose-derived stem cells (ASCs (Allogeneic Expanded)).