Immunosuppressive Cytokine Secretion

Immunosuppressive cytokine secretion is a biological process by which immune cells release cytokines that dampen or suppress immune responses. Key cytokines involved include IL-10, TGF-β, and IL-35, primarily produced by regulatory T cells and monocytes/macrophages. This process is crucial for maintaining immune homeostasis, preventing autoimmunity, and limiting tissue damage during inflammation. However, dysregulation can contribute to pathological immunosuppression or unchecked inflammation. Targeting this process, by either inhibiting or augmenting it, holds therapeutic potential for cancer, autoimmune diseases, and transplant rejection.

Other names

Anti-inflammatory cytokine secretionImmunoregulatory cytokine secretion

Not applicable, this is a biological process not a target.