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Improved insulin sensitivity refers to an increased responsiveness of the body's cells to the hormone insulin, facilitating glucose uptake and utilization. It is a therapeutic goal for preventing or managing metabolic disorders like type 2 diabetes. Modulation is achieved through lifestyle changes (exercise, diet, weight loss) and pharmacological interventions that enhance insulin signaling or reduce insulin resistance.
Indirectly achieved through various mechanisms including increased GLUT4 translocation, enhanced insulin signaling, reduced hepatic glucose production, and improved beta-cell function.
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