Indium-111 ion (Indium-111 (In-111))

Indium-111 ion is a radioactive isotope of indium used extensively in nuclear medicine as a radiotracer for imaging. It emits gamma photons at energies of 171 and 245 keV and has a physical half-life of approximately 2.8 days (67.9 hours). Clinically, it is incorporated into compounds such as Indium In-111 oxyquinoline to label autologous leukocytes, enabling the detection and localization of infections or inflammation via scintigraphy. It is also used in other complexes (e.g., Indium In-111 pentetate) for cisternography and tumor imaging. The ion itself is not a biological target, and its use is strictly diagnostic. Key safety concerns include handling precautions for radiation and potential mislabeling in clinical settings. If a biological target is sought (e.g., a receptor, transporter), "Indium-111 ion" is not appropriate. Instead, reference should be made to the cellular or molecular structure labeled with Indium-111 for imaging purposes (for example, labeled monoclonal antibodies, leukocytes).

Other names

Indium-111In-111Indium radioisotopeIndium In-111Indium In-111 pentetateIndium In-111 oxyquinoline

Not applicable for drugs targeting this molecule. Mechanism for diagnostic agent: emits gamma rays (171–245 keV) upon decay by electron capture, enabling imaging with gamma camera.