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Target intelligence / Profile preview
Indocyanine Green (ICG)
- Target
- ICG
- Molecular classification
- Small molecule, Tricarbocyanine dye, Contrast Agent, Fluorophore
01
Overview
Indocyanine green (ICG) is a water-soluble, tricarbocyanine fluorescent dye widely used in medical diagnostics. It is primarily utilized as a non-targeting contrast agent for optical imaging. It binds tightly to plasma proteins after intravenous administration and remains confined within the vascular system. It has a short half-life and is exclusively removed from circulation by the liver into bile without undergoing metabolism.
- Other names
- IC-GreenCardio-GreenFox GreenIR 125NK 1611
02
Mechanism of action
Binds to plasma proteins; remains confined to the vasculature; excreted via the liver into bile without undergoing metabolism.
03
Biological functions
Dye for cardiac output measurementDye for hepatic function assessmentDye for ophthalmic angiographyVascular visualizationLymph node mappingTumor identificationOrgan perfusion assessmentPhotosensitizer
04
Disease associations
Cancer (tumor visualization)Cardiovascular disease (cardiac output)Liver disease (hepatic function)Ophthalmological diseases (angiography)
05
Safety considerations
Rare allergic reactions
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