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Inflammatory cytokine levels
- Molecular classification
- Other (as a group descriptor), Cytokines, Proteins
01
Overview
"Inflammatory cytokine levels" generally refers to the quantification of cytokines such as interleukins (e.g., IL-1β, IL-6), interferons (e.g., IFN-γ), and tumor necrosis factors (e.g., TNF-α) in biological fluids. These proteins are released by immune and non-immune cells and coordinate responses to infection, injury, and disease. Changes in their levels are used as biomarkers for inflammation, infection, autoimmunity, and cancer but do not themselves represent a therapeutic target; rather, individual cytokines and their receptors do[1][3][5].
- Other names
- Pro-inflammatory cytokinesCytokine concentrationsInflammatory cytokine profileCytokine mediators of inflammation
02
Biological functions
Immune responseSignal transductionRegulation of inflammationCell proliferationCell deathApoptosis
03
Disease associations
InflammationAutoimmune diseaseInfectionCancerCardiovascular diseaseMetabolic disease
04
Safety considerations
Immunosuppression (from targeting cytokine pathways)Increased infection riskOff-target inflammation or autoimmunity
05
Biomarkers
IL-6 serum concentrationTNF-α plasma levelIL-1βInterferon gamma
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