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Inflammatory mediator expression in intestinal smooth muscle

Molecular classification: Other

Overview

Inflammatory mediator expression in intestinal smooth muscle describes the inducible production and secretion of cytokines (e.g., IL-1β, IL-6, TNF-α), chemokines, and other inflammatory molecules by smooth muscle cells of the gastrointestinal tract in response to stimuli such as infection, injury, or immune activation. This process plays a key role in the pathogenesis and symptoms of inflammatory bowel diseases by altering muscle contractility and gut motility, and by contributing to local and systemic inflammation.

Biological functions

Immune responseSignal transduction

Disease associations

Inflammation

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