Inflammatory mediators and cells

“Inflammatory mediators and cells” refers collectively to the wide spectrum of molecules (such as cytokines, chemokines, prostaglandins, eicosanoids, acute-phase proteins) and cell types (such as macrophages, neutrophils, lymphocytes, mast cells, dendritic cells, myeloid-derived suppressor cells) that orchestrate inflammatory responses. Inflammatory mediators include pro-inflammatory molecules (e.g., TNF-α, IL-1β, IL-6, IFN-γ, chemokines) and anti-inflammatory molecules (e.g., IL-10, TGF-β), which are released by specific cell types to regulate immune activity, recruit other immune cells, induce tissue repair, or drive pathological inflammation[1][6][7]. The cells themselves serve as primary sources or effectors in response to infections, trauma, or immunological triggers. Importantly, “inflammatory mediators and cells” is a generic term encompassing numerous distinct molecular and cellular entities, each of which may themselves be considered drug targets, diagnostic biomarkers, or disease mediators in specific contexts[1][3][6][7]. Therefore, as written, the target definition is too broad and non-specific for structured molecular annotation.

Other names

inflammatory mediatorsimmune cellsinflammatory cells