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Influenza Hemagglutinin Protein (H7) (None)
- Target
- None
- Molecular classification
- Glycoprotein, Viral Surface Protein, Hemagglutinin
01
Overview
Influenza hemagglutinin H7 enables virus entry through dual roles: recognizing sialic acid receptors on host cells via its globular head domain—and facilitating membrane fusion through pH-triggered conformational changes primarily involving its stem region. Its high variability drives immune evasion but also makes it an essential focus for surveillance efforts against emerging zoonotic threats like avian-origin H7N9 strains.
02
Mechanism of action
Inhibition of receptor binding; Inhibition of membrane fusion
03
Biological functions
Receptor bindingMembrane fusionViral entryAntigen presentation
04
Disease associations
InfectionInfluenzaZoonotic disease
05
Safety considerations
Antigenic driftAntigenic shiftPotential for zoonotic transmissionElicitation of antibody-dependent enhancement (ADE)
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