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Target intelligence / Profile preview
Influenza Virus Antigen
- Molecular classification
- Glycoprotein
01
Overview
Influenza virus antigens are the molecular components of the influenza virus recognized by the immune system. Key antigens include the surface glycoproteins hemagglutinin (HA) and neuraminidase (NA), which mediate viral entry and release, respectively, and are primary targets for neutralizing antibodies. Antigenic variability in HA and NA underlies the challenges in developing long-lasting immunity against influenza infections.
- Other names
- Hemagglutinin (HA)Neuraminidase (NA)Matrix proteins (M1)Ion channel protein (M2)Nucleoprotein (NP)Polymerase subunits (PB1, PB2, PA)
02
Mechanism of action
Neuraminidase inhibitors prevent the release of new virions from infected cells.
03
Biological functions
Host cell bindingMembrane fusionVirion releaseImmune recognitionViral entry
04
Disease associations
Infection
05
Safety considerations
Antigenic driftAntigenic shiftStrain-specific immunityPotential for cross-species transmission
06
Interacting drugs
Oseltamivir
1 more in the full profile.
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