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Inhibition of neuroinflammation is a therapeutic strategy aimed at suppressing inflammatory processes within the central nervous system (CNS). It involves targeting key molecular pathways and mediators involved in glial cell activation and the production of pro-inflammatory molecules. The goal is to reduce neuronal damage and slow the progression of various neurological disorders, while balancing efficacy with the preservation of beneficial immune functions.
Inhibition of signaling pathways (NF-κB, MAPK, JAK/STAT), modulation of microglial/astrocyte activity, reduction of pro-inflammatory mediator production (cytokines, chemokines, ROS/RNS)
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