Inhibitory synaptic factor 2A (INSYN2A)

Inhibitory synaptic factor 2A (INSYN2A) is a protein that participates in the machinery of inhibitory synapses, acting likely as a scaffold to help organize synaptic components. It is predicted to play a role in postsynaptic inhibitory signaling, likely at GABAergic synapses, helping to dampen neuronal activity and maintain proper synaptic inhibition in the central nervous system. Expression of INSYN2A is enriched in various brain regions, particularly those with significant inhibitory neurotransmission such as the hippocampus, cortex, and basal ganglia. Its specific molecular mechanisms and any roles outside of the nervous system remain subjects of ongoing research. There are no approved drugs or common clinical applications linked to this protein as of present data, and its relevance as a disease gene or biomarker is not established.

Other names

INSYN2AInhibitory synaptic factor 2AInhibitory synaptic protein 2C10orf141FAM196AINSYN2InSyn2FLJ45557Family with sequence similarity 196 member A