INO80 complex subunit D (INO80D)

INO80 complex subunit D (INO80D) is a regulatory component of the **INO80 chromatin remodeling complex** in humans[3]. The INO80 complex is a multisubunit ATP-dependent chromatin remodeling complex that functions in *transcriptional regulation*, *DNA replication*, and *DNA repair* by altering chromatin structure[1][3]. INO80D is considered a subunit without direct catalytic or targeting receptor/enzyme function; rather, it helps mediate the assembly and regulation of the complex[3]. The INO80 complex plays crucial roles in maintaining genome stability, regulating the placement of histone variants such as H2A.Z, and supporting cell cycle progression and chromosome segregation[1][2]. Although dysfunction of the INO80 complex is linked to genome instability and cancer, INO80D itself is generally not recognized as a direct therapeutic drug target, but its role as part of the chromatin remodeling complex underpins important cellular processes essential for normal cell function[1][2][3].

Other names

FLJ20309INO80D