Target intelligence / Profile preview

INO80D antisense RNA 1 (INO80D-AS1)

Target
INO80D-AS1
Molecular classification
Long non-coding RNA (lncRNA), Antisense RNA
01

Overview

INO80D antisense RNA 1 is a long non-coding RNA gene located antisense to the protein-coding INO80D gene. Like other antisense lncRNAs, INO80D-AS1 may regulate the expression or function of its sense partner gene (INO80D), potentially playing a role in cellular gene regulation. A related lncRNA (CR933609) is shown to act as a decoy to protect INO80D from miRNA-mediated downregulation in non-small cell lung cancer cells, suggesting that antisense or regulatory lncRNAs in this genomic region may influence cancer biology. However, specific biological functions, disease links, and therapeutic relevance of INO80D-AS1 itself remain largely uncharacterized in current biomedical literature. There are no known clinically approved drugs, biomarkers, or direct safety concerns associated with this RNA. In summary, INO80D-AS1 is an antisense lncRNA, not a canonical drug target, and primarily classified under gene regulatory functions with a possible, but yet unconfirmed, role in cancer biology.

Other names
AC007383.2INO80D-AS2
02

Mechanism of action

None reported — lncRNAs such as INO80D-AS1 are typically not direct drug targets, and no established mechanisms of action for drugs binding or modulating INO80D-AS1 are available.

03

Biological functions

Regulation of gene expression (potentially of INO80D)Other regulatory roles typical of lncRNAs (possible chromatin or transcriptional regulation inferred)
04

Disease associations

Cancer (possible implication via regulation of INO80D in non-small cell lung cancer (NSCLC))Other (potential regulatory roles not yet fully defined)

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