Target intelligence / Profile preview

Myo-inositol-1-phosphate synthase (None)

Target
None
Molecular classification
Enzyme
01

Overview

Myo-inositol-1-phosphate synthase is a key enzyme in the biosynthesis of myo-inositol, catalyzing the first and rate-limiting step of this pathway. It converts D-glucose 6-phosphate into 1L-myo-inositol 1-phosphate in a NAD+-dependent manner. This reaction is essential for the production of all inositol-containing compounds, which are critical for various cellular processes including cell growth, oxidative stress resistance, and synthesis of signaling molecules.

Other names
Ino-1ISYNA1Myo-inositol phosphate synthaseInositol-3-phosphate synthase 1
02

Mechanism of action

Catalyzes the conversion of D-glucose 6-phosphate to 1L-myo-inositol 1-phosphate.

03

Biological functions

Myo-inositol biosynthesisCell growthOxidative stress protectionPrecursor synthesis for phosphatidylinositol lipids and signaling molecules
04

Disease associations

Oxidative stress related diseasesMetabolic disorders (impaired inositol metabolism)

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