Integrin subunit beta 1 pseudogene 1 (ITGB1P1)

Integrin subunit beta 1 pseudogene 1 (ITGB1P1) is a processed pseudogene related to the integrin beta 1 gene family[1][5][7]. Pseudogenes are nonfunctional gene copies or gene fragments that generally do not code for proteins, though in some cases pseudogenes can have regulatory RNA functions at the transcript level[2]. ITGB1P1 does not encode an active integrin protein or contribute to integrin-mediated cell signaling or adhesion functions. Due to naming similarities, ITGB1P1 is often confused with ITGB1 (Integrin subunit beta 1), which is a genuine cell surface receptor involved in a variety of cellular processes[7]. Instead, ITGB1P1 is currently annotated as non-functional, with no direct therapeutic or biomarker use, and should not be considered a therapeutic target[1][5]. If you are seeking information on a druggable integrin (such as integrin beta 1), you should refer to “Integrin subunit beta 1” (ITGB1), not ITGB1P1.

Other names

FNRBLITGB1L