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Inter-alpha-trypsin inhibitor heavy chain family member 6 pseudogene

Molecular classification: Pseudogene

Overview

The ENSG00000275387 locus represents the pseudogene for inter-alpha-trypsin inhibitor heavy chain family member 6 (ITIH6), a non-coding genomic element. Unlike the ITIH6 protein-coding gene, it does not produce a functional protein and thus is not considered a therapeutic target. Functional ITIH6 (not this pseudogene) belongs to a family of proteins involved in extracellular matrix stabilization and is linked to inflammation, immunity, and tumorigenesis, but the pseudogene variant itself is generally non-functional and is excluded from drug targeting or diagnostic applications[4][1][2].

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