Intercellular communication via exosomal cargo delivery

Intercellular communication via exosomal cargo delivery" refers to the biological process by which cells exchange information through the release and uptake of exosomes—small extracellular vesicles containing proteins, lipids, and nucleic acids. These exosomes are formed within multivesicular bodies inside donor cells before being secreted into body fluids. Upon reaching recipient cells, their molecular contents can modulate cellular functions such as gene expression or immune responses. This mechanism is fundamental to both normal physiology and various diseases; for example, tumor-derived exosomes can promote cancer progression by altering the behavior of surrounding or distant cells. The field is rapidly evolving with interest in harnessing this system for targeted drug delivery; however, "intercellular communication via exosomal cargo delivery" describes a complex biological pathway rather than a single molecule or receptor target suitable for direct pharmacological intervention.

Other names

Exosome-mediated intercellular communicationExosomal cargo transferExtracellular vesicle (EV) cargo delivery