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Target intelligence / Profile preview
Interferon omega (IFN-ω)
- Target
- IFN-ω
- Molecular classification
- Cytokine, Type I Interferon
01
Overview
Interferon omega (IFN-ω) is a type I interferon cytokine involved in immune regulation and antiviral defense. It binds to the IFNAR receptor complex and activates the JAK/STAT signaling pathway, leading to antiviral, antiproliferative, and immunomodulatory effects. It has veterinary applications for treating viral infections in animals but remains investigational for human use.
- Other names
- Interferon omega 1IFNW1
02
Mechanism of action
Binds to the type I interferon receptor (IFNAR) complex, activating the JAK/STAT signaling pathway.
03
Biological functions
Antiviral responseAntitumor activityImmunomodulationStimulation of NK cell activityEnhancement of MHC class I expression
04
Disease associations
Viral infectionsCancerAutoimmune diseases (e.g., primary sclerosing cholangitis)
05
Safety considerations
Species-specific biological activityPotential for immunogenicityFurther clinical trials needed for human therapy
06
Interacting drugs
Recombinant feline interferon omega (Virbagen Omega)
1 more in the full profile.
07
Biomarkers
IFN-ω levels in serum or tissue (e.g., in PSC)
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