Interferon omega 1 pseudogene 18 (IFNWP18)

Interferon omega 1 pseudogene 18 (IFNWP18) is a human pseudogene located on chromosome 9 and is a non-functional, processed copy of a type I interferon omega gene[2][3]. Pseudogenes such as IFNWP18 do not produce functional proteins and are generally regarded as evolutionary remnants of formerly active genes. While type I interferons—including IFN-ω—are key cytokines in innate antiviral and anticancer immune responses, IFNWP18 itself is not transcribed or translated into a protein with biological activity[2][3][6]. It is referenced in genomic databases and belongs to a family with other IFN omega pseudogenes, but there is no evidence of any direct role in disease, therapy, or drug interactions. Additional context: - The functional counterpart (IFN-ω1) is an active type I interferon and a cytokine involved in innate immunity, but IFNWP18 specifically is not this protein and does not share its signaling or disease relevance[1][3]. - Recent research into pseudogenes suggests some pseudogenes may have regulatory RNA roles or epigenetic effects, but no such evidence has been reported for IFNWP18[6]. Summary: IFNWP18 is a pseudogene, not a protein-coding therapeutic target, and does not have established biological, disease, or therapeutic relevance.

Other names

pseudo-IFN-alpha-mLEIF-Minterferon, omega 18 (pseudogene)pseudo-IFN-alpha-m processed pseudogeneIFNWP18