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Interleukin 1 family member 10 (IL-1F10), also known as IL-38, is a secreted protein that belongs to the interleukin-1 cytokine family, which plays roles in modulating immune and inflammatory responses. IL-1F10 is structurally related to other interleukin-1 family molecules but has distinct sequence features. Its biological function is not fully elucidated, but evidence suggests it may play a role in anti-inflammatory signaling and immune modulation, similar to IL-37 and IL-1 receptor antagonists. Clinical relevance is emerging, with research investigating its potential in autoimmune and inflammatory diseases, but no approved drugs or established therapies directly target IL-1F10/IL-38 yet[3].
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