Interleukin-17 receptor E-like protein (IL17REL)

Interleukin-17 receptor E-like protein (IL17REL) is a predicted member of the interleukin-17 receptor family, with sequence homology to other IL-17 receptors, and is presumed to enable interleukin-17 receptor activity[5][3]. While IL17REL's precise function in humans is not fully characterized, it is predicted to be involved in cytokine-mediated signaling based on its gene structure and family membership[5][3]. The IL-17 receptor family mediates pro-inflammatory responses and immune system signaling, especially in host defense and certain autoimmune diseases[1]. IL17REL (gene symbol: IL17REL, NCBI Gene ID: 400935) is listed as a protein-coding gene but lacks well-established disease associations or pharmacological targeting at this time[5][3]. The full-length protein is referenced by UniProt accession Q6ZVW7[5]. No approved drugs or compounds are listed as interacting directly with IL17REL. Drugs targeting the broader IL-17 pathway (e.g., Brodalumab for IL-17RA) exist, but no specific agents for IL17REL are described[1]. In summary, IL17REL is a predicted cytokine receptor with homology to interleukin-17 receptor family members, but its unique biological role and clinical relevance remain under-studied and largely speculative[5][3][1].

Other names

Interleukin-17 receptor E-likeIL17RELIL-17 receptor E-likeIL-17RE-likeFLJ41993Putative interleukin-17 receptor E-like protein

Null. No specific drugs targeting IL17REL; mechanisms of action are undefined.